NCBI Accession #
NP_201212.1
NCBI GenBank Nucleotide #
NM_125803.4
NCBI Official Full Name
phosphatidylinositol 4-OH kinase beta1
NCBI Official Symbol
PI-4KBETA1
NCBI Official Synonym Symbols
MHJ24.5; MHJ24_5; phosphatidylinositol 4-OH kinase beta1; PHOSPHATIDYLINOSITOL 4-OH KINASE BETA1; PI4KBETA1
NCBI Protein Information
phosphatidylinositol 4-OH kinase beta1
NCBI Summary
Encodes a phosphatidylinositol 4-OH kinase, PI-4Kbeta1. Arabidopsis contains 12 PI-4Ks in three separate families: PI-4Kalphs, PI-4kbeta, and PI-4Kgamma. PI-4Kbeta1 is 83% identical to PI-4kbeta2 encoded by At5g09350. Interacts with the RabA4b GTPase. Important for polarized root hair growth as the loss of this gene and its close relative PI-4kbeta2, leads to the formation of abnormal root hairs.
UniProt Synonym Gene Names
PI4K; PI4KBETA1; PI4-kinase beta 1; PtdIns-4-kinase beta 1; AtPI4Kbeta1; PI-4Kbeta1
UniProt Protein Name
Phosphatidylinositol 4-kinase beta 1
UniProt Synonym Protein Names
Phosphatidylinositol 4-OH kinase beta1; AtPI4Kbeta1; PI-4Kbeta1
UniProt Primary Accession #
Q9FMJ0
UniProt Secondary Accession #
Q9ZPE1
UniProt Related Accession #
Q9FMJ0
UniProt Comments
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate. Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB2, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB2 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway.