NCBI Accession #
NP_187096.2
NCBI GenBank Nucleotide #
NM_111317.3
NCBI Official Full Name
Peroxisome biogenesis protein 12
NCBI Official Symbol
PEX12
NCBI Official Synonym Symbols
ABERRANT PEROXISOME MORPHOLOGY 4; APM4; ATPEX12; peroxin-12; PEROXIN-12; PEX12; T27C4.11; T27C4_11
NCBI Protein Information
Peroxisome biogenesis protein 12
NCBI Summary
RING finger protein involved in peroxisome biogenesis. Also involved in peroxisomal import of nitric oxide synthase.
UniProt Synonym Gene Names
APM4; AtPEX12
UniProt Protein Name
Peroxisome biogenesis protein 12
UniProt Synonym Protein Names
Peroxin-12; AtPEX12; Pex12p; Protein ABERRANT PEROXISOME MORPHOLOGY 4
UniProt Entry Name
PEX12_ARATH
UniProt Primary Accession #
Q9M841
UniProt Secondary Accession #
Q8GYG2
UniProt Related Accession #
Q9M841
UniProt Comments
Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5.