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Peptidyl-prolyl cis-trans isomerase FKBP65 (FKBP65), Recombinant Protein
Cat: RP06822
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Peptidyl-prolyl cis-trans isomerase FKBP65 (FKBP65) , partial
Product Gene Name
FKBP65 recombinant protein
Product Synonym Gene Name
FKBP65
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
65,223 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Peptidyl-prolyl cis-trans isomerase
NCBI/Uniprot Data
NCBI Accession #
NP_199668.1
NCBI GI #
15239016
NCBI GenBank Nucleotide #
NM_124233.3
NCBI GeneID
834913
NCBI Official Full Name
FKBP-type peptidyl-prolyl cis-trans isomerase family protein
NCBI Official Symbol
AT5G48570
NCBI Official Synonym Symbols
ATFKBP65; FKBP65; K15N18.12; K15N18_12; ROF2
NCBI Protein Information
FKBP-type peptidyl-prolyl cis-trans isomerase family protein
NCBI Summary
Encodes one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
UniProt Gene Name
FKBP65
UniProt Synonym Gene Names
ROF2; PPIase FKBP65; AtFKBP65
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP65
UniProt Synonym Protein Names
70 kDa peptidyl-prolyl isomerase; FK506-binding protein 65; AtFKBP65; Immunophilin FKBP65; Peptidyl-prolyl isomerase ROF2; Protein ROTAMASE FKBP 2; Rotamase
UniProt Primary Accession #
Q9FJL3
UniProt Secondary Accession #
Q0WSA8; B9DGC2
UniProt Related Accession #
Q9FJL3
UniProt Comments
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Co-chaperone that negatively modulates thermotolerance by interacting with FKBP62 and decreasing the HSFA2-mediated accumulation of chaperones of the small-HSPs family. Plays a positive role in tolerance to intracellular acid stress by maintaining the pH homeostasis. May be a part of transcription regulation pathways upon pathogen infection.
For research use only, not for clinical use.