Products
Online Inquiry
Peptidyl-prolyl cis-trans isomerase FKBP62 (FKBP62), Recombinant Protein
Cat: RP06691
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Peptidyl-prolyl cis-trans isomerase FKBP62 (FKBP62) , partial
Product Gene Name
FKBP62 recombinant protein
Product Synonym Gene Name
FKBP62
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
61,453 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Peptidyl-prolyl cis-trans isomerase
NCBI/Uniprot Data
NCBI Accession #
NP_189160.3
NCBI GI #
30687816
NCBI GenBank Nucleotide #
NM_113429.5
NCBI GeneID
822117
NCBI Official Full Name
rotamase FKBP 1
NCBI Official Symbol
ROF1
NCBI Official Synonym Symbols
ATFKBP62; FK506 BINDING PROTEIN 62; FKBP62; rotamase FKBP 1
NCBI Protein Information
rotamase FKBP 1
NCBI Summary
Encodes a a high molecular weight member of the FK506 binding protein (FKBP) family. It has three FKBP12-like domains, tetratricopeptide repeats, and a putative calmodulin binding domain. Modulates thermotolerance by interacting with HSP90.1 and affecting the accumulation of HsfA2-regulated sHSPs. Belongs to one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
UniProt Gene Name
FKBP62
UniProt Synonym Gene Names
ROF1; PPIase FKBP62; AtFKBP62
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP62
UniProt Synonym Protein Names
70 kDa peptidyl-prolyl isomerase; FK506-binding protein 62; AtFKBP62; Immunophilin FKBP62; Peptidylprolyl isomerase ROF1; Protein ROTAMASE FKBP 1; Rotamase
UniProt Primary Accession #
Q38931
UniProt Secondary Accession #
Q38949; Q9LSF3
UniProt Related Accession #
Q38931
UniProt Comments
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides . Co-chaperone that positively modulates thermotolerance by interacting with HSP90.1 and increasing the HSFA2-mediated accumulation of chaperones of the small-HSPs family.
For research use only, not for clinical use.