NCBI Accession #
NP_567098.2
NCBI GenBank Nucleotide #
NM_115901.4
NCBI Official Full Name
FKBP-like peptidyl-prolyl cis-trans isomerase family protein
NCBI Official Symbol
AT3G60370
NCBI Protein Information
FKBP-like peptidyl-prolyl cis-trans isomerase family protein
NCBI Summary
Encodes an immunophilin, FKBP20-2, that belongs to the FK-506 binding protein (FKBP) subfamily functioning as peptidyl-prolyl isomerases (PPIases) in protein folding. FKBP20-2 has a unique pair of cysteines at the C terminus and was found to be reduced by thioredoxin (Trx) (itself reduced by NADPH by means of NADP-Trx reductase). The FKBP20-2 protein, which contains only two of the five amino acids required for catalysis, showed a low level of PPIase activity that was unaffected on reduction by Trx. Genetic disruption of the FKBP20-2 gene provide evidence that FKBP20-2 participates specifically in the accumulation of the PSII supercomplex in the chloroplast thylakoid lumen by means of a mechanism that has yet to be determined.
UniProt Gene Name
FKBP20-2
UniProt Synonym Gene Names
AtFKBP20-2
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP20-2, chloroplastic
UniProt Synonym Protein Names
FK506-binding protein 20-2
UniProt Primary Accession #
Q0WRJ7
UniProt Secondary Accession #
Q9M222
UniProt Related Accession #
Q0WRJ7
UniProt Comments
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides . Involved in the accumulation of the PSII complex.