NCBI Accession #
NP_565381.1
NCBI GenBank Nucleotide #
NM_127141.3
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
NCBI Official Synonym Symbols
CYCLOPHILIN 40; CYCLOPHILIN-40; CYP40; F19G14.21; F19G14_21; SQUINT
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
NCBI Summary
SQN encodes the Arabidopsis homolog of cyclophilin 40 (CyP40). It is specifically required for the vegetative but not the reproductive maturation of the shoot. Belongs to one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
UniProt Synonym Gene Names
SQN; PPIase CYP40; Cyclophilin-40
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase CYP40
UniProt Synonym Protein Names
Cyclophilin of 40 kDa; Cyclophilin-40; Protein SQUINT; Rotamase CYP40
UniProt Primary Accession #
Q9C566
UniProt Secondary Accession #
Q08A80; Q9XIL2
UniProt Related Accession #
Q9C566
UniProt Comments
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in promoting the expression of the juvenile phase of vegetative development, and, to a lower extent, in regulating the positioning of floral buds, floral morphogenesis and the expression of HSPs.