NCBI Accession #
NP_001190299.1
NCBI GenBank Nucleotide #
NM_001203370.1
NCBI Official Full Name
cyclophilin 20-2
NCBI Official Symbol
Pnsl5
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA CYCLOPHILIN 20-2; ATCYP20-2; cyclophilin 20-2; CYP20-2; Photosynthetic NDH subcomplex L 5; T19L5.80; T19L5_80
NCBI Protein Information
cyclophilin 20-2
NCBI Summary
Encodes a lumenal cyclophilin with peptidyl-prolyl isomerase activity that is associated with the NAD(P)H dehydrogenase complex in stromal regions of the thylakoid membrane. It is likely to be important for the accumulation of the hydrophobic domain of the NAD(P)H dehydrogenase complex. This complex is associated with PSI and is responsible for the reduction of plastoquinone.
UniProt Synonym Gene Names
PPIase CYP20-2; TLP20
UniProt Protein Name
Photosynthetic NDH subunit of lumenal location 5, chloroplastic
UniProt Synonym Protein Names
Cyclophilin of 20 kDa 2; Peptidyl-prolyl cis-trans isomerase CYP20-2 (EC:5.2.1.8); PPIase CYP20-2; Rotamase CYP20-2; Thylakoid lumen PPIase of 20 kDa; TLP20
UniProt Primary Accession #
Q9ASS6
UniProt Secondary Accession #
Q53YK9; Q8L9L5; Q9FY98; F4K2G0
UniProt Related Accession #
Q9ASS6
UniProt Comments
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Responsible, with FKBP13, for all PPIase activity observed in thylakoid lumen. Modulates the conformation of BZR1, which regulates flowering (PubMed:16765949, PubMed:23897924).