NCBI Accession #
NP_001077978.1
NCBI GenBank Nucleotide #
NM_001084509.1
NCBI Official Full Name
cyclophilin 5
NCBI Official Symbol
CYP5
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA CYCLOPHILIN 5; ATCYP5; CYCLOPHILIN 19-4; cyclophilin 5; CYP19-4; F23F1.12; F23F1_12
NCBI Protein Information
cyclophilin 5
NCBI Summary
encodes a cyclophilin protein that exhibits peptidylprolyl cis/trans-isomerase and protein refolding activities that were sensitive to cyclosporin A. The protein interacts with GNOM in vitro and is localized to both the cytosolic and membrane fractions. The gene is expressed in the developing embryo.
UniProt Gene Name
CYP19-4
UniProt Synonym Gene Names
CYP5; PPIase CYP19-4
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase CYP19-4
UniProt Synonym Protein Names
Cyclophilin of 19 kDa 4; Cyclophilin-5; Rotamase CYP19-4
UniProt Primary Accession #
Q8LDP4
UniProt Secondary Accession #
O22515; O80876; A8MS66
UniProt Related Accession #
Q8LDP4
UniProt Comments
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved during embryogenesis and organ development by regulating the folding of EMB30/GNOM, and thus, by modulating its activity.