NCBI Accession #
NP_196363.1
NCBI GenBank Nucleotide #
NM_120828.4
NCBI Official Full Name
peptidemethionine sulfoxide reductase 2
NCBI Official Symbol
PMSR2
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA METHIONINE SULFOXIDE REDUCTASE 2; ATMSRA2; peptidemethionine sulfoxide reductase 2; T2I1.170; T2I1_170
NCBI Protein Information
peptidemethionine sulfoxide reductase 2
NCBI Summary
ubiquitous enzyme that repairs oxidatively damaged proteins. Methionine sulfoxide reductase activity. Mutant lacking reductase activity showed increased protein oxidation, nitration and glycation of specific amino acid residues during darkness.
UniProt Synonym Gene Names
PMSR2; AtMSRA2; Peptide Met(O) reductase
UniProt Protein Name
Peptide methionine sulfoxide reductase A2
UniProt Synonym Protein Names
Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase; Protein-methionine-S-oxide reductase
UniProt Primary Accession #
Q9LY15
UniProt Related Accession #
Q9LY15
UniProt Comments
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. Prevents cellular oxidative damage in long nights. MSRA family specifically reduces the MetSO S-enantiomer.