Pattern formation protein EMB30 (EMB30), Recombinant Protein
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Pattern formation protein EMB30 (EMB30), Recombinant Protein

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Cat: RP05448
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Pattern formation protein EMB30 (EMB30) , partial
Product Gene Name
EMB30 recombinant protein
Product Synonym Gene Name
EMB30
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
162,619 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Metallothionein-like protein

NCBI/Uniprot Data

NCBI Accession #
NP_001184991.1
NCBI GI #
334182567
NCBI GenBank Nucleotide #
NM_001198062.1
NCBI GeneID
837958
NCBI Official Full Name
sec7 domain-containing protein
NCBI Official Symbol
GN
NCBI Official Synonym Symbols
EMB30; EMBRYO DEFECTIVE 30; F16A14.20; GNOM; VAN7; VASCULAR NETWORK 7
NCBI Protein Information
sec7 domain-containing protein
NCBI Summary
Encodes a GDP/GTP exchange factor for small G-proteins of the ADP ribosylation factor (RAF) class, and as regulator of intracellular trafficking. Homologous to Sec7p and YEC2 from yeast. Involved in the specification of apical-basal pattern formation. Essential for cell division, expansion and adhesion. It appears that heteotypic binding between the DCB and C-terminal domains of two GNOM proteins is required for membrane association, however, GNOM appears to exist predominantly as a heterodimer formed through DCB-DCB interactions.
UniProt Gene Name
GN
UniProt Synonym Gene Names
EMB30; GBF3; MIZ2; VAN7
UniProt Protein Name
ARF guanine-nucleotide exchange factor GNOM
UniProt Synonym Protein Names
Pattern formation protein EMB30; Protein EMBRYO DEFECTIVE 30; Protein MIZU-KUSSEI2; Protein VASCULAR NETWORK 7
UniProt Primary Accession #
Q42510
UniProt Secondary Accession #
Q38883; Q56ZY3
UniProt Related Accession #
Q42510
UniProt Comments
Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of endosomal vesicle trafficking but is also involved in the endocytosis process. Could function redundantly with GNL1 in the retrograde Golgi to endoplasmic reticulum trafficking. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the sorting of PIN1 from endosomal compartments to the basal plasma membrane and the polarization of PIN3 to the bottom side of hypocotyl endodermal cells. Involved in the specification of apical-basal pattern formation in the early embryo and during root formation. Required for correct cell wall organization leading to normal cell adhesion during seedling development. Plays also an essential role in hydrotropism of seedling roots.

For research use only, not for clinical use.