NCBI Accession #
NP_171752.1
NCBI GenBank Nucleotide #
NM_100132.2
NCBI Official Full Name
two-pore potassium channel 4
NCBI Official Symbol
TPK4
NCBI Official Synonym Symbols
ATKCO4; ATTPK4; CA2+ ACTIVATED OUTWARD RECTIFYING K+ CHANNEL 4; KCO4; T14P4.16; T14P4_16; TPK4
NCBI Protein Information
two-pore potassium channel 4
NCBI Summary
Encodes AtTPK4, a member of the Arabidopsis thaliana K+ channel family of AtTPK/KCO proteins. AtTPK4 is targeted to the plasma membrane. In contrast other members of the AtTPK proteins are located in tonoplast. AtTPK4 forms a voltage-independent K+ channel that is blocked by extracellular calcium ions. May form homomeric ion channels in vivo.
UniProt Synonym Gene Names
KCO4; AtTPK4; AtKCO4
UniProt Protein Name
Two-pore potassium channel 4
UniProt Synonym Protein Names
Outward-rectifying potassium channel 4; AtKCO4
UniProt Entry Name
KCO4_ARATH
UniProt Primary Accession #
Q9FWX6
UniProt Secondary Accession #
Q6X308
UniProt Related Accession #
Q9FWX6
UniProt Comments
Voltage-independent, instantaneously activating, potassium-selective plasma membrane ion channel. Open rectifier. Regulated by cytoplasmic pH and extra-cellular calcium. Has some permeability for Rb+ and NH4+, but none for Na+ or Li+.