Nuclear cap-binding protein subunit 2 (CBP20), Recombinant Protein
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Nuclear cap-binding protein subunit 2 (CBP20), Recombinant Protein

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Cat: RP04166
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 2 (CBP20)
Product Gene Name
CBP20 recombinant protein
Product Synonym Gene Name
CBP20
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MASLFKEQAK LSAYRDRRFS GTQEEFDEAL RASTTVYIGN VSFYTTEEQL YELFSRAGEI KKIIMGLDKN TKTPCGFCFV LFYSREDTED AVKYISGTIL DDRPIRVDFD WGFQEGRQWG RGRSGGQVRD EYRTDYDPAR GGYGKLVQKE LEAQRQLVDY GTGSLGAYPQ AAPTNYGNGR RGGGNYGQGG QNRHGRGDYH RKRQRDDDRY GRDNSRRNTD HESRRDTDSD MRPEKNPRFR ESGDSDDDGE DDRKRRS
Sequence Positions
1-257, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
29,609 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_001078705.1
NCBI GI #
145334719
NCBI GenBank Nucleotide #
NM_001085236.2
NCBI GeneID
834443
NCBI Official Full Name
CAP-binding protein 20
NCBI Official Symbol
CBP20
NCBI Official Synonym Symbols
ATCBP20; CAP-binding protein 20; MLN1.12; MLN1_12
NCBI Protein Information
CAP-binding protein 20
NCBI Summary
Encodes a nuclear cap-binding protein that forms a heterodimeric complex with ABH1 (ATCBP80) and is likely to participate in RNA metabolism. Its mRNA is ubiquitously expressed.Loss of function mutations suggest a role in processing of pri-miRNA and mRNA splicing.
UniProt Gene Name
CBP20
UniProt Synonym Gene Names
AtCBP20
UniProt Protein Name
Nuclear cap-binding protein subunit 2
UniProt Synonym Protein Names
20 kDa nuclear cap-binding protein; NCBP 20 kDa subunit; AtCBP20
UniProt Primary Accession #
Q9XFD1
UniProt Related Accession #
Q9XFD1
UniProt Comments
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. CBP20 also plays a role in stabilization of ABH1/CBP80 and ABH1/CBP80 localization to the nucleus. Involved in flowering regulation via its interaction with FRIGIDA.

For research use only, not for clinical use.