NCBI Accession #
NP_191681.1
NCBI GenBank Nucleotide #
NM_115986.4
NCBI Official Full Name
NAD(P)-binding Rossmann-fold superfamily protein
NCBI Official Symbol
SDR1
NCBI Official Synonym Symbols
short-chain dehydrogenase/reductase 1
NCBI Protein Information
NAD(P)-binding Rossmann-fold superfamily protein
NCBI Summary
CytADR/SDR1 is an aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on alpha,beta-unsaturated aldehydes with more than 5 carbons in vitro. It can also act on menthone and neomenthol in vitro, but these do not represent likely endogenous activities of this enzyme in planta. GFP-tagged CytADR appears to localize to the cytosol where it likely plays a role in detoxifying reactive carbonyls. sdr1 mutants have altered responses to pathogens.
UniProt Synonym Gene Names
AtSDR1
UniProt Protein Name
(+)-neomenthol dehydrogenase
UniProt Synonym Protein Names
Menthone:neomenthol reductase; Short-chain dehydrogenase/reductase 1; AtSDR1
UniProt Primary Accession #
Q9M2E2
UniProt Related Accession #
Q9M2E2
UniProt Comments
Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons (PubMed:21169366). Involved in basal resistance against pathogens.