NCBI Accession #
NP_194750.1
NCBI GenBank Nucleotide #
NM_119167.4
NCBI Official Full Name
P450 reductase 2
NCBI Official Symbol
ATR2
NCBI Official Synonym Symbols
AR2; F9N11.60; F9N11_60; P450 reductase 2
NCBI Protein Information
P450 reductase 2
NCBI Summary
Encodes NADPH-cytochrome P450 reductase that catalyzes the first oxidative step of the phenylpropanoid general pathway.
UniProt Synonym Gene Names
AR2; CPR 2; P450R 2
UniProt Protein Name
NADPH--cytochrome P450 reductase 2
UniProt Primary Accession #
Q9SUM3
UniProt Secondary Accession #
Q39036; F4JPK2
UniProt Related Accession #
Q9SUM3
UniProt Comments
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and dichloroindophenol.