NAC domain-containing protein 8 (NAC008), Recombinant Protein
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NAC domain-containing protein 8 (NAC008), Recombinant Protein

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Cat: RP06686
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana NAC domain-containing protein 8 (NAC008)
Product Gene Name
NAC008 recombinant protein
Product Synonym Gene Name
NAC008
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAGRSWLIDS NRIATKIMSA SASSDPRQVV WKSNPSRHCP KCQHVIDNSD VVDDWPGLPR GVKFDPSDPE IIWHLLAKSG LSGLSSHPFI DEFIPTVNQD DGICYTHPKN LPGVKSDGTV SHFFHKAIKA YSTGTRKRRK IHDDDFGDVR WHKTGRTKPV VLDGVQRGCK KIMVLYGGKA VKTNWVMHQY HLGIEEDEKE GDYVVSKIFY QQPQQLVVKR GDKAEQEVSE DIFAAVTPTA DPVTPKLATP EPRNAVRICS DSHIASDYVT PSDYVSAHEV SLAETSEVMC MEDEVQSIQP NHERPSSGPE LEHGLENGAK EMLDDKEEQE KDRDNENQGE EDPTWFDSGS QFILNSQQLV EALSLCDDLL GSQDREENTN SGSLKDKQPC IADYAHLGPE DFKRDLEECQ KIVLDPSNIE LDTPPEFRLS QLEFGSQDSF LAWGTGKTD
Sequence Positions
1-449, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
50,289 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
NAC domain-containing protein

NCBI/Uniprot Data

NCBI Accession #
NP_564238.2
NCBI GI #
30689293
NCBI GenBank Nucleotide #
NM_102369.3
NCBI GeneID
839145
NCBI Official Full Name
NAC (No Apical Meristem) domain transcriptional regulator superfamily protein
NCBI Official Symbol
SOG1
NCBI Official Synonym Symbols
ANAC008; Arabidopsis NAC domain containing protein 8; F2J7.1; SUPPRESSOR OF GAMMA RADIATION 1
NCBI Protein Information
NAC (No Apical Meristem) domain transcriptional regulator superfamily protein
NCBI Summary
Encodes suppressor of gamma response 1 (SOG1), a putative transcription factor governing multiple responses to DNA damage.
UniProt Gene Name
SOG1
UniProt Synonym Gene Names
ANAC008
UniProt Protein Name
SUPPRESSOR OF GAMMA RESPONSE 1
UniProt Synonym Protein Names
NAC domain-containing protein 8
UniProt Primary Accession #
Q6NQK2
UniProt Secondary Accession #
Q9C610; Q9C6M7
UniProt Related Accession #
Q6NQK2
UniProt Comments
Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress.

For research use only, not for clinical use.