NCBI Accession #
NP_563814.1
NCBI GenBank Nucleotide #
NM_100710.4
NCBI Official Full Name
decapping 1
NCBI Official Symbol
DCP1
NCBI Official Synonym Symbols
ATDCP1; decapping 1
NCBI Protein Information
decapping 1
NCBI Summary
Encodes DCP1 involved in mRNA decapping. DCP1 forms a mRNA decapping complex with DCP2 (At5g13570) and VCS (VARICOSE) (At3g13300). However, unlike DCP2, DCP1 itself does not have mRNA decapping activity in vitro. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP2.
UniProt Gene Name
At1g08370
UniProt Protein Name
mRNA-decapping enzyme-like protein
UniProt Synonym Protein Names
DCP1 homolog
UniProt Primary Accession #
Q9SJF3
UniProt Secondary Accession #
O64895
UniProt Related Accession #
Q9SJF3
UniProt Comments
As a component of the decapping complex, involved in the degradation of mRNAs. Essential for postembryonic development.