NCBI Accession #
NP_565885.1
NCBI GenBank Nucleotide #
NM_129383.3
NCBI Official Full Name
CAX-interacting protein 2
NCBI Official Symbol
CXIP2
NCBI Official Synonym Symbols
ATGRX2; AtGRXS16; CAX-interacting protein 2; F16M14.20; F16M14_20; GLUTAREDOXIN; glutaredoxin 16; GLUTAREDOXIN 2
NCBI Protein Information
CAX-interacting protein 2
NCBI Summary
Encodes protein homologous to CXIP1. CXIP1 is a PICOT domain containing protein interacts with CAX1, a high capacity calcium transporter. However, CXP2 does not interact with CAX1 and only moderately activates another calcium transporter CAX4.
UniProt Synonym Gene Names
AtGrxS16
UniProt Protein Name
Bifunctional monothiol glutaredoxin-S16, chloroplastic
UniProt Synonym Protein Names
Atypical GIY-YIG endonuclease
UniProt Primary Accession #
Q8H7F6
UniProt Secondary Accession #
O80451; Q8LD13
UniProt Related Accession #
Q8H7F6
UniProt Comments
May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins (Probable). The GRXS16-BOLA1 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster (PubMed:24714563). Able to cleave linearized DNA in vitro (PubMed:23690600).