NCBI Accession #
NP_564001.1
NCBI GenBank Nucleotide #
NM_101519.3
NCBI Official Full Name
molybdenum cofactor sulfurase (LOS5) (ABA3)
NCBI Official Symbol
ABA3
NCBI Official Synonym Symbols
ABA DEFICIENT 3; ACI2; ALTERED CHLOROPLAST IMPORT 2; ATABA3; AtLOS5; F19K19.13; F19K19_13; LOS5; LOW OSMOTIC STRESS 5; MOLYBDENUM COFACTOR SULFURASE; SIR3; SIRTINOL RESISTANT 3
NCBI Protein Information
molybdenum cofactor sulfurase (LOS5) (ABA3)
NCBI Summary
Encodes molybdenum cofactor sulfurase. Involved in Moco biosynthesis. Involved in the conversion of ABA-aldehyde to ABA, the last step of abscisic acid (ABA) biosynthesis. sir loss-of-function mutants are resistant to sirtinol, a modulator of auxin signaling.N terminal domain is similar to bacterial NifS suggesting a common mechanism for sulphur mobilization and transfer. Also involved in protein import into chloroplasts.
UniProt Synonym Gene Names
LOS5; MCS; MOS; MoCo sulfurase
UniProt Protein Name
Molybdenum cofactor sulfurase
UniProt Synonym Protein Names
Abscisic acid protein 3; Low expression of osmotically expressive genes protein 5; Molybdenum cofactor sulfurtransferase
UniProt Primary Accession #
Q9C5X8
UniProt Secondary Accession #
Q9FX72
UniProt Related Accession #
Q9C5X8
UniProt Comments
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. Modulates cold stress- and osmotic stress-responsive gene expression by acting as key regulator of abscisic acid (ABA) biosynthesis.