NCBI Accession #
NP_179335.3
NCBI GenBank Nucleotide #
NM_127298.5
NCBI Official Full Name
Seven transmembrane MLO family protein
NCBI Official Symbol
MLO7
NCBI Official Synonym Symbols
ATMLO7; F5J6.19; F5J6_19; MILDEW RESISTANCE LOCUS O 7; NORTIA; NTA
NCBI Protein Information
Seven transmembrane MLO family protein
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. Controls pollen tube reception in synergids. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO7 belongs to the clade III, with AtMLO5, AtMLO8, AtMLO9, and AtMLO10. The gene is expressed in vegetative organs (RT-PCR experiments)and in pollen grains, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Synonym Gene Names
NTA; AtMlo7
UniProt Protein Name
MLO-like protein 7
UniProt Synonym Protein Names
Protein NORTIA
UniProt Primary Accession #
O22752
UniProt Secondary Accession #
Q94KB6
UniProt Related Accession #
O22752
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins . Controls pollen tube reception in the female gametophyte synergids.