NCBI Accession #
NP_176350.1
NCBI GenBank Nucleotide #
NM_104836.1
NCBI Official Full Name
MLO-like protein 6
NCBI Official Symbol
MLO6
NCBI Official Synonym Symbols
ATMLO6; MILDEW RESISTANCE LOCUS O 6; MLO6; T25B24.9; T25B24_9
NCBI Protein Information
MLO-like protein 6
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of cotyledons, young leaves and petals, in mature rosette leaves, in anthers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Synonym Gene Names
AtMlo6
UniProt Protein Name
MLO-like protein 6
UniProt Entry Name
MLO6_ARATH
UniProt Primary Accession #
Q94KB7
UniProt Secondary Accession #
Q9SY94
UniProt Related Accession #
Q94KB7
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins .