NCBI Accession #
NP_564257.1
NCBI GenBank Nucleotide #
NM_102433.1
NCBI Official Full Name
MLO-like protein 14
NCBI Official Symbol
MLO14
NCBI Official Synonym Symbols
ATMLO14; MILDEW RESISTANCE LOCUS O 14; MLO14; T24P13.8; T24P13_8
NCBI Protein Information
MLO-like protein 14
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO14 belongs to the clade I, with AtMLO4 and AtMLO11. The gene is expressed during early seedling growth, in developing primary root, and particularly in root tips of 10-day old seedlings; it was not expressed in leaves or flowers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Synonym Gene Names
AtMlo14
UniProt Protein Name
MLO-like protein 14
UniProt Entry Name
MLO14_ARATH
UniProt Primary Accession #
Q94KB1
UniProt Secondary Accession #
Q9LQY2
UniProt Related Accession #
Q94KB1
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins .