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MLO-like protein 12 (MLO12), Recombinant Protein
Cat: RP06198
Size: 0.02 mg/ 0.1 mg/ 5x0.1 mg
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana MLO-like protein 12 (MLO12)
Product Gene Name
MLO12 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAIKERSLEE TPTWAVAVVC FVLLFISIMI EYFLHFIGHW FKKKHKKALS EALEKVKAEL MLLGFISLLL VVLQTPVSEI CIPRNIAATW HPCSNHQEIA KYGKDYIDDG RKILEDFDSN DFYSPRRNLA TKGYDKCAEK GKVALVSAYG IHQLHIFIFV LAVFHVLYCI ITYALGKTKM KKWKSWERET KTIEYQYAND PERFRFARDT SFGRRHLNIW SKSTFTLWIT CFFRQFFGSV TKVDYLTLRH GFIMAHLPAG SAARFDFQKY IERSLEQDFT VVVGISPLIW CIAVLFILTN THGWDSYLWL PFLPLIVILI VGAKLQMIIS KLGLRIQEKG DVVKGAPVVE PGDDLFWFGR PRFILFLIHL VLFTNAFQLA FFVWSTYEFT LKNCFHHKTE DIAIRITMGV LIQVLCSYIT LPLYALVTQM GTSMRPTIFN DRVANALKKW HHTAKKQTKH GHSGSNTPHS SRPTTPTHGM SPVHLLHNYN NRSLDQQTSF TASPSPPRFS DYSGQGHGHQ HFFDPESQNH SYQREITDSE FSNSHHPQVD MASPVREEKE IVEHVKVDLS EFTFKK
Sequence Positions
1-576aa; full length protein
Format
Liquid containing glycerol
Host
Cell Free Expression
Molecular Weight
66,548 Da
Storage
Store at -20℃, for extended storage, conserve at -20℃ or -80℃.Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Protein Family
MLO-like protein
NCBI/Uniprot Data
NCBI Accession #
NP_565902.1
NCBI GI #
18404979
NCBI GenBank Nucleotide #
NM_129478.4
NCBI GeneID
818505
NCBI Official Full Name
protein MILDEW RESISTANCE LOCUS O 12
NCBI Official Symbol
MLO12
NCBI Official Synonym Symbols
ATMLO12; MILDEW RESISTANCE LOCUS O 12; MLO12; T16B24.16; T16B24_16
NCBI Protein Information
protein MILDEW RESISTANCE LOCUS O 12
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in root tips and cotyledon vascular system, in floral organs (anthers and stigma), and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Gene Name
MLO12
UniProt Synonym Gene Names
AtMlo12; AtMlo18
UniProt Protein Name
MLO-like protein 12
UniProt Entry Name
MLO12_ARATH
UniProt Primary Accession #
O80961
UniProt Secondary Accession #
Q94KB3
UniProt Related Accession #
O80961
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins .
For research use only, not for clinical use.