NCBI Accession #
NP_001032070.1
NCBI GenBank Nucleotide #
NM_001036993.2
NCBI Official Full Name
Seven transmembrane MLO family protein
NCBI Official Symbol
MLO11
NCBI Official Synonym Symbols
ATMLO11; MGN6.12; MGN6_12; MILDEW RESISTANCE LOCUS O 11
NCBI Protein Information
Seven transmembrane MLO family protein
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO11 belongs to the clade I, with AtMLO4 and AtMLO14. The gene is expressed during early seedling growth (in primary root), in root tips and lateral root primordia, and in very young leaves, and in flowers and fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Synonym Gene Names
AtMlo11
UniProt Protein Name
MLO-like protein 11
UniProt Primary Accession #
Q9FI00
UniProt Related Accession #
Q9FI00
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins .