NCBI Accession #
NP_201398.1
NCBI GenBank Nucleotide #
NM_125994.2
NCBI Official Full Name
Seven transmembrane MLO family protein
NCBI Official Symbol
MLO10
NCBI Official Synonym Symbols
ATMLO10; K2A18.3; K2A18_3; MILDEW RESISTANCE LOCUS O 10
NCBI Protein Information
Seven transmembrane MLO family protein
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO10 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO8, and AtMLO9. The gene is expressed in root and cotyledon vascular system, in root-shoot junction and lateral root primordia and in developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s
UniProt Synonym Gene Names
AtMlo10
UniProt Protein Name
MLO-like protein 10
UniProt Primary Accession #
Q9FKY5
UniProt Related Accession #
Q9FKY5
UniProt Comments
May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins .