MKK1, Recombinant Protein
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MKK1, Recombinant Protein

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Cat: RP03742
Size: 0.05 mg/ 0.1 mg/ 5x0.1 mg
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Mouse-ear cress MKK1 protein, N-Fc Tag
Product Synonym Names
AtMKK1; Mitogen-activated protein kinase kinase 1; MKK1; NMAPKK; MAP kinase kinase 1; AtMEK1; MEK1
Product Gene Name
MKK1 recombinant protein
Purity
>90% as determined by SDS-PAGE
Format
Lyophilized. Lyophilized from PBS pH 7.4, 5% Trehalose, 5% Mannose, 1mM EDTA.
Host
Mammalian cells
Molecular Weight
34,087 Da
Storage
Store at 2 to 8℃ for one week. Store at -20 to -80℃ for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.In general, proteins are provided as lyophilized powder or frozen liquid. They are shipped out with dry ice or blue ice unless customers require otherwise.
Protein Family
MAP kinase kinase

NCBI/Uniprot Data

NCBI Accession #
AAB97145.1
NCBI GI #
2196704
NCBI GeneID
828713
NCBI Official Full Name
MEK1
NCBI Official Symbol
MEK1
NCBI Official Synonym Symbols
ATMEK1; F20B18.180; F20B18_180; MAP kinase/ ERK kinase 1; MEK1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MKK1; NMAPKK
NCBI Protein Information
mitogen-activated protein kinase kinase 1
NCBI Summary
Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4, in response to stress. Gets phosphorylated by MEKK1 in response to wounding.
UniProt Gene Name
MKK1
UniProt Synonym Gene Names
MEK1; AtMKK1; MAP kinase kinase 1
UniProt Protein Name
Mitogen-activated protein kinase kinase 1
UniProt Synonym Protein Names
AtMEK1; NMAPKK
UniProt Entry Name
M2K1_ARATH
UniProt Primary Accession #
Q94A06
UniProt Secondary Accession #
O04440; O04661
UniProt Related Accession #
Q94A06
UniProt Comments
MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination.

For research use only, not for clinical use.