Mitogen-activated protein kinase kinase 5 (MKK5), Recombinant Protein
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Mitogen-activated protein kinase kinase 5 (MKK5), Recombinant Protein

Cat: RP01504
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Mitogen-activated protein kinase kinase 5 (MKK5)
Product Gene Name
MKK5 recombinant protein
Product Synonym Gene Name
MKK5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MKPIQSPSGV ASPMKNRLRK RPDLSLPLPH RDVALAVPLP LPPPSSSSSA PASSSAISTN ISAAKSLSEL ERVNRIGSGA GGTVYKVIHT PTSRPFALKV IYGNHEDTVR RQICREIEIL RSVDHPNVVK CHDMFDHNGE IQVLLEFMDQ GSLEGAHIWQ EQELADLSRQ ILSGLAYLHR RHIVHRDIKP SNLLINSAKN VKIADFGVSR ILAQTMDPCN SSVGTIAYMS PERINTDLNH GRYDGYAGDV WSLGVSILEF YLGRFPFAVS RQGDWASLMC AICMSQPPEA PATASQEFRH FVSCCLQSDP PKRWSAQQLL QHPFILKATG GPNLRQMLPP PRPLPSAS
Sequence Positions
1-348, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
38,329 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Mitogen-activated protein kinase kinase

NCBI/Uniprot Data

NCBI Accession #
NP_001319606.1
NCBI GI #
1063712879
NCBI GenBank Nucleotide #
NM_001338511.1
NCBI GeneID
821676
NCBI Official Full Name
MAP kinase kinase 5
NCBI Official Symbol
MKK5
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5; ATMAP2K_ALPHA; ATMEK5; ATMKK5; MAP kinase kinase 5; MAP KINASE KINASE 5; MAP2K_A; MEK5
NCBI Protein Information
MAP kinase kinase 5
NCBI Summary
Encodes a mitogen-activated kinase kinase, dual specific protein kinase that is expressed in vegetative tissues and floral buds. Involved in innate immunity. This protein activates MPK3/MPK6 and early-defense genes redundantly with MKK4.In plants with both MKK5 and MKK6 levels reduced by RNAi plants, floral organs do not abscise suggestion a role for both proteins in mediating floral organ abscission.
UniProt Gene Name
MKK5
UniProt Synonym Gene Names
MEK5; AtMAP2Kalpha; AtMEK5; AtMKK5; MAP kinase kinase 5
UniProt Protein Name
Mitogen-activated protein kinase kinase 5
UniProt Primary Accession #
Q8RXG3
UniProt Secondary Accession #
O80398; Q96517
UniProt Related Accession #
Q8RXG3
UniProt Comments
Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the morphology of plant organs. MKK4 and MKK5 participate in the regulation of floral organ abscission. Target of the Pseudomonas syringae type III effector HopF2, that inhibits the activation of the downstream MPK6 and PAMP-triggered immunity. Plays a critical role in high light stress tolerance by the mediation of the Cu/Zn SODs CSD1 and CSD2 gene expression. Phosphorylates BZR1 in vitro.

For research use only, not for clinical use.