Mitogen-activated protein kinase kinase 1 (MKK1), Recombinant Protein
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Mitogen-activated protein kinase kinase 1 (MKK1), Recombinant Protein

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Cat: RP01521
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Mitogen-activated protein kinase kinase 1 (MKK1)
Product Gene Name
MKK1 recombinant protein
Product Synonym Gene Name
MKK1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MNRGSLCPNP ICLPPLEQSI SKFLTQSGTF KDGDLRVNKD GIQTVSLSEP GAPPPIEPLD NQLSLADLEV IKVIGKGSSG NVQLVKHKLT QQFFALKVIQ LNTEESTCRA ISQELRINLS SQCPYLVSCY QSFYHNGLVS IILEFMDGGS LADLLKKVGK VPENMLSAIC KRVLRGLCYI HHERRIIHRD LKPSNLLINH RGEVKITDFG VSKILTSTSS LANSFVGTYP YMSPERISGS LYSNKSDIWS LGLVLLECAT GKFPYTPPEH KKGWSSVYEL VDAIVENPPP CAPSNLFSPE FCSFISQCVQ KDPRDRKSAK ELLEHKFVKM FEDSDTNLSA YFTDAGSLIP PLAN
Sequence Positions
1-354, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
34,087 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
MAP kinase kinase

NCBI/Uniprot Data

NCBI Accession #
NP_194337.1
NCBI GI #
15236108
NCBI GenBank Nucleotide #
NM_118740.3
NCBI GeneID
828713
NCBI Official Full Name
MAP kinase/ ERK kinase 1
NCBI Official Symbol
MEK1
NCBI Official Synonym Symbols
ATMEK1; F20B18.180; F20B18_180; MAP kinase/ ERK kinase 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MKK1; NMAPKK
NCBI Protein Information
MAP kinase/ ERK kinase 1
NCBI Summary
Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4, in response to stress. Gets phosphorylated by MEKK1 in response to wounding.
UniProt Gene Name
MKK1
UniProt Synonym Gene Names
MEK1; AtMKK1; MAP kinase kinase 1
UniProt Protein Name
Mitogen-activated protein kinase kinase 1
UniProt Synonym Protein Names
AtMEK1; NMAPKK
UniProt Primary Accession #
Q94A06
UniProt Secondary Accession #
O04440; O04661
UniProt Related Accession #
Q94A06
UniProt Comments
MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination.

For research use only, not for clinical use.