Methyl-CpG-binding domain-containing protein 6 (MBD6), Recombinant Protein
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Methyl-CpG-binding domain-containing protein 6 (MBD6), Recombinant Protein

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Cat: RP02651
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Methyl-CpG-binding domain-containing protein 6 (MBD6)
Product Gene Name
MBD6 recombinant protein
Product Synonym Gene Name
MBD6
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSDSVAGDFP PDPLLASGAF ISSAGDGTLD SSAKRRPIQG GIGISGSGES VRIGMANGTD QVNHQTESKS RKRAAPGDNW LPPGWRVEDK IRTSGATAGS VDKYYYEPNT GRKFRSRTEV LYYLEHGTSK RGTKKAENTY FNPDHFEGQG SNRVTRTATV PPPPPPPLDF DFKNPPDKVS WSMANAGEEG WIPNIGDVKV QDSVRRDWST AFTFITSRNP SKVSA
Sequence Positions
1-225, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
24,450 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Methyl-CpG-binding domain protein

NCBI/Uniprot Data

NCBI Accession #
NP_200746.1
NCBI GI #
15238389
NCBI GenBank Nucleotide #
NM_125329.4
NCBI GeneID
836057
NCBI Official Full Name
methyl-CPG-binding domain 6
NCBI Official Symbol
MBD6
NCBI Official Synonym Symbols
ATMBD6; F2O15.4; F2O15_4; methyl-CPG-binding domain 6
NCBI Protein Information
methyl-CPG-binding domain 6
NCBI Summary
Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins.
UniProt Gene Name
MBD6
UniProt Synonym Gene Names
AtMBD6; MBD06
UniProt Protein Name
Methyl-CpG-binding domain-containing protein 6
UniProt Synonym Protein Names
Methyl-CpG-binding protein MBD6
UniProt Primary Accession #
Q9LTJ1
UniProt Related Accession #
Q9LTJ1
UniProt Comments
Transcriptional regulator that binds CpG, CpNpN and CpNpG (N is A, T, or C) islands in promoters regardless the DNA methylation status. Plays probably a role in gene silencing. May associate with histone deacetylase proteins (HDAC). Required for nucleolar dominance that consist in the silencing of rRNA genes inherited from one progenitor in genetic hybrids. Recruited to rRNA genes in a DRM2-dependent manner.

For research use only, not for clinical use.