NCBI Accession #
NP_182049.1
NCBI GenBank Nucleotide #
NM_130087.4
NCBI Official Full Name
methionine aminopeptidase 1A
NCBI Official Symbol
MAP1A
NCBI Official Synonym Symbols
F4L23.25; methionine aminopeptidase 1A
NCBI Protein Information
methionine aminopeptidase 1A
NCBI Summary
Encodes a cytoplasmic MAP1 like methionine aminopeptidase which is involved in removing the N-terminal methionine from proteins. Induced mutants using RNAi technology which knocks out both MAP1 and MAP2 like genes show abnormal development.
UniProt Synonym Gene Names
MAP 1A; MetAP 1A
UniProt Protein Name
Methionine aminopeptidase 1A
UniProt Synonym Protein Names
Peptidase M 1A
UniProt Primary Accession #
Q9SLN5
UniProt Secondary Accession #
Q548T6; Q8LAQ1
UniProt Related Accession #
Q9SLN5
UniProt Comments
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).