NCBI Accession #
NP_181477.1
NCBI GenBank Nucleotide #
NM_129503.3
NCBI Official Full Name
putative Mn-specific cation diffusion facilitator transporter
NCBI Official Symbol
MTP11
NCBI Official Synonym Symbols
ATMTP11; F12L6.11; F12L6_11; MTP11
NCBI Protein Information
putative Mn-specific cation diffusion facilitator transporter
NCBI Summary
Encodes a Golgi-localized manganese transporter that is involved in Mn tolerance. When expressed into yeast cells, this gene confer Mn2+ and Cu2+ tolerance.
UniProt Synonym Gene Names
AtMTP11
UniProt Protein Name
Metal tolerance protein 11
UniProt Entry Name
MTP11_ARATH
UniProt Primary Accession #
O80632
UniProt Secondary Accession #
B9DI01
UniProt Related Accession #
O80632
UniProt Comments
Function: Cation/proton antiporter involved in endogenous manganese tolerance probably through vesicular trafficking and exocytosis.Subcellular location: Prevacuolar compartment membrane. Golgi apparatus membrane; Multi-pass membrane protein. Tissue specificity: Widely expressed.Disruption phenotype: Increased accumulation of manganese and hypersensitivity to elevated levels of manganese.Sequence similarities: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.