NCBI Accession #
NP_001031711.1
NCBI GenBank Nucleotide #
NM_001036634.1
NCBI Official Full Name
metacaspase 2
NCBI Official Synonym Symbols
AtMC2; AtMCP1c; F24A6.7; MCP1c; metacaspase 1c; metacaspase 2
NCBI Protein Information
metacaspase 2
NCBI Summary
Encodes a type I metacaspase. Two Arabidopsis metacaspases, AT1G02170 (MC1) and AT4G25110 (MC2) antagonistically control programmed cell death in Arabidopsis. MC1 is a positive regulator of cell death and requires conserved caspase-like putative catalytic residues for its function. MC2 negatively regulates cell death. This function is independent of the putative catalytic residues. A third type I Arabidopsis metacaspase is MC3 (AT5g64240).
UniProt Synonym Gene Names
MCP1C; AtMC2; AtMCP1c
UniProt Protein Name
Metacaspase-2
UniProt Synonym Protein Names
Metacaspase 1c; AtMCP1c
UniProt Primary Accession #
Q7XJE5
UniProt Secondary Accession #
Q682S4; Q9SW15
UniProt Related Accession #
Q7XJE5
UniProt Comments
Acts as a negative regulator of oxidative stress cell death and hypersensitive cell death response mediated by immune response. Acts via indirect or direct regulation of AMC1 at postranscriptional level.