NCBI Accession #
NP_001078469.1
NCBI GenBank Nucleotide #
NM_001085000.2
NCBI Official Full Name
Mnd1 family protein
NCBI Official Symbol
ATMND1
NCBI Official Synonym Symbols
F19B15.200; F19B15_200
NCBI Protein Information
Mnd1 family protein
NCBI Summary
A homolog of yeast, mouse and human mnd1delta protein. Null mutants exhibit normal vegetative and flower development; however, during prophase I, chromosomes become fragmented resulting in random distribution of the fragments between polyads. Both male and female meiosis are defective and strong accumulation of AtRAD51 was observed in the inflorescence nuclei of mutant plants. Similarly to its yeast and animal homologues, AtMnd1 might play a role in DSB repair during meiosis.
UniProt Synonym Gene Names
AtMND1
UniProt Protein Name
Meiotic nuclear division protein 1 homolog
UniProt Synonym Protein Names
Meiotic nuclear division 1-like protein
UniProt Primary Accession #
Q8GYD2
UniProt Secondary Accession #
Q9SZE5; A8MS27
UniProt Related Accession #
Q8GYD2
UniProt Comments
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1/LIM15- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.