Mediator of RNA polymerase II transcription subunit 21 (MED21), Recombinant Protein
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Mediator of RNA polymerase II transcription subunit 21 (MED21), Recombinant Protein

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Cat: RP04823
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Mediator of RNA polymerase II transcription subunit 21 (MED21)
Product Gene Name
MED21 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDIISQLQEQ VNTIAAITFN AFGTLQRDAP PVQLSPNYPE PPATTTVTDD ATPFPEQPKQ LSAGLVKAAK QFDALVAALP LSEGGEGAQL KRIAELQVEN DLVGQELQKQ LEAAEKELKQ VQELFGQAAD NCLNMKKPE
Sequence Positions
1-139, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
15,041 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Putative mediator of RNA polymerase II transcription

NCBI/Uniprot Data

NCBI Accession #
NP_192387.2
NCBI GI #
334186358
NCBI GenBank Nucleotide #
NM_116716.5
NCBI GeneID
825815
NCBI Official Full Name
mediator 21
NCBI Official Symbol
MED21
NCBI Official Synonym Symbols
mediator 21; T4B21.8; T4B21_8
NCBI Protein Information
mediator 21
NCBI Summary
Encodes the med21 subunit of the mediator complex which is involved in transcriptional regulation. MED21 interacts physically with the E3 ligase HUB1 and this interaction may be important in mediation defense responses to fungal pathogens.
UniProt Gene Name
MED21
UniProt Synonym Gene Names
MED21_1; SRB7
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 21
UniProt Synonym Protein Names
Mediator complex subunit 21; RNAPII complex component SRB7
UniProt Primary Accession #
C0LU16
UniProt Secondary Accession #
Q84WP9; Q9M0Z8; Q9ZS95
UniProt Related Accession #
C0LU16
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for embryo development and defense against necrotrophic fungal pathogens.

For research use only, not for clinical use.