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Mediator of RNA polymerase II transcription subunit 13 homolog (GCT), Recombinant Protein
Cat: RP00361
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Mediator of RNA polymerase II transcription subunit 13 homolog (GCT) , partial
Product Gene Name
GCT recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
217,269 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_001185237.1
NCBI GI #
334183337
NCBI GenBank Nucleotide #
NM_001198308.1
NCBI GeneID
841978
NCBI Official Full Name
RNA polymerase II transcription mediator
NCBI Official Symbol
GCT
NCBI Official Synonym Symbols
CCT; CENTER CITY; GRAND CENTRAL; MAB2; MACCHI-BOU 2
NCBI Protein Information
RNA polymerase II transcription mediator
NCBI Summary
Encodes the Arabidopsis homolog of the transcriptional regulator MED13, is dynamically expressed during embryogenesis and regulates both developmental timing and the radial pattern formation.
UniProt Gene Name
MED13
UniProt Synonym Gene Names
GCT; MAB2; MED13_1
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 13
UniProt Synonym Protein Names
Protein GRAND CENTRAL; Protein MACCHI-BOU 2
UniProt Primary Accession #
F4I096
UniProt Secondary Accession #
Q9C8A3; F4I095
UniProt Related Accession #
F4I096
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts closely together with MAB12. Involved in the regulation of embryo patterning and cotyledon organogenesis. May act through transient repression of specific genes such as the ones responsive to auxin.
For research use only, not for clinical use.