NCBI Accession #
NP_176116.2
NCBI GenBank Nucleotide #
NM_104601.2
NCBI Official Full Name
MSCS-like 3
NCBI Official Symbol
MSL3
NCBI Official Synonym Symbols
F16M22.2; F16M22_2; MSCS-like 3
NCBI Protein Information
MSCS-like 3
NCBI Summary
A member of MscS-like gene family, structurally very similar to MSL2, comprising of an N-terminal chloroplast transit peptide, five trans-membrane helices and a C-terminal cytoplasmic domain. Mutant plants showed abnormalities in the size and shape of plastids. MSL3-GFP was localized to discrete foci on the plastid envelope and co-localize with the plastid division protein AtMinE. MSL3 was capable of increasing the osmotic-shock survival of a mutant bacterial strain lacking MS-ion-channel activity.
UniProt Protein Name
Mechanosensitive ion channel protein 3, chloroplastic
UniProt Synonym Protein Names
Mechanosensitive channel of small conductance-like 3; MscS-Like protein 3
UniProt Primary Accession #
Q8L7W1
UniProt Secondary Accession #
Q9C6R0; Q9C731
UniProt Related Accession #
Q8L7W1
UniProt Comments
Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Controls plastid size, shape, and perhaps division during normal plant development by altering ion flux in response to changes in membrane tension. Acts as a component of the chloroplast division machinery.