NCBI Accession #
NP_001031171.1
NCBI GenBank Nucleotide #
NM_001036094.1
NCBI Official Full Name
alpha-mannosidase 1
NCBI Official Symbol
MNS1
NCBI Official Synonym Symbols
alpha-mannosidase 1; ALPHA-MANNOSIDASE IB; F5D21.1; F5D21_1; MANIB
NCBI Protein Information
alpha-mannosidase 1
NCBI Summary
Encodes an alpha-mannosidase I enzyme responsible for N-glycan maturation.
UniProt Synonym Gene Names
MANIB; AtMANIb
UniProt Protein Name
Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1
UniProt Synonym Protein Names
Alpha-mannosidase IB
UniProt Primary Accession #
Q9C512
UniProt Secondary Accession #
Q2V4H4
UniProt Related Accession #
Q9C512
UniProt Comments
Class I alpha-mannosidase essential for early N-glycan processing. Progressively trim alpha-1,2-linked mannose residues. Produces Man5GlcNAc2 from Man8GlcNAc2, but only Man6GlcNAc2 from Man9GlcNAc2. Have difficulty acting on the terminal mannose of the b-branch. Involved in root development and cell wall biosynthesis.