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Lysine-specific histone demethylase 1 homolog 3 (FLD), Recombinant Protein
Cat: RP00243
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Lysine-specific histone demethylase 1 homolog 3 (FLD) , partial
Product Gene Name
FLD recombinant protein
Product Synonym Gene Name
FLD
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
86,037 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein FLOWERING LOCUS
NCBI/Uniprot Data
NCBI Accession #
NP_001326316.1
NCBI GI #
1063710611
NCBI GenBank Nucleotide #
NM_001337874.1
NCBI GeneID
820202
NCBI Official Full Name
protein FLOWERING locus D-like protein
NCBI Official Symbol
FLD
NCBI Official Synonym Symbols
FLOWERING LOCUS D; Reduced Systemic immunity 1; RSI1
NCBI Protein Information
protein FLOWERING locus D-like protein
NCBI Summary
Encodes a plant homolog of a SWIRM domain containing protein found in histone deacetylase complexes in mammals. Lesions in FLD result in hyperacetylation of histones in FLC chromatin, up-regulation of FLC expression and extremely delayed flowering. FLD plays a key role in regulating the reproductive competence of the shoot and results in different developmental phase transitions in Arabidopsis.
UniProt Gene Name
FLD
UniProt Synonym Gene Names
SOF1
UniProt Protein Name
Protein FLOWERING LOCUS D
UniProt Synonym Protein Names
Protein SUPPRESSOR OF OVEREXPRESSED FCA 1
UniProt Primary Accession #
Q9CAE3
UniProt Secondary Accession #
Q58T18; Q9SS50; F4J3R3
UniProt Related Accession #
Q9CAE3
UniProt Comments
Probable histone demethylase that promotes flowering independently of the photoperiod and vernalization pathways by repressing FLOWERING LOCUS C (FLC), a floral repressor that blocks the transition from vegetative to reproductive development. Probably mediates histone H3 'Lys-4' demethylation at FLC locus. Seems to act in partial redundancy with LDL1 and LDL2 to repress FLC expression. Required for histone H4 deacetylation of FLC locus. May be a component of the histone deacetylase complex.
For research use only, not for clinical use.