Lysine-specific histone demethylase 1 homolog 1 (LDL1), Recombinant Protein
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Lysine-specific histone demethylase 1 homolog 1 (LDL1), Recombinant Protein

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Cat: RP01806
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Lysine-specific histone demethylase 1 homolog 1 (LDL1) , partial
Product Gene Name
LDL1 recombinant protein
Product Synonym Gene Name
LDL1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
93,312 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_176471.1
NCBI GI #
15221606
NCBI GenBank Nucleotide #
NM_104961.4
NCBI GeneID
842582
NCBI Official Full Name
LSD1-like 1
NCBI Official Symbol
LDL1
NCBI Official Synonym Symbols
ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE; ATLSD1; ATSWP1; F23N19.21; F23N19_21; LSD1; LSD1-like 1; LYSINE-SPECIFIC HISTONE DEMETHYLASE; SWP1
NCBI Protein Information
LSD1-like 1
NCBI Summary
Encodes a homolog of human Lysine-Specific Demethylase1. Involved in H3K4 methylation of target genes including the flowering time loci FLC and FWA. Located in nucleus. Negatively regulates root elongation. Involved in repression of LRP1 via histone deacetylation.
UniProt Gene Name
LDL1
UniProt Protein Name
Lysine-specific histone demethylase 1 homolog 1
UniProt Synonym Protein Names
Flavin-containing amine oxidase domain-containing protein 1; Protein LSD1-LIKE 1
UniProt Primary Accession #
Q8VXV7
UniProt Secondary Accession #
Q56WM3; Q9SI68
UniProt Related Accession #
Q8VXV7
UniProt Comments
Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA (PubMed:17921315). Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression (PubMed:17921315). Required for cytosine methylation of FWA (PubMed:17921315). Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes (PubMed:25852712).

For research use only, not for clinical use.