NCBI Accession #
NP_001318610.1
NCBI GenBank Nucleotide #
NM_001343669.1
NCBI Official Full Name
EF-TU receptor
NCBI Official Synonym Symbols
EF-TU receptor; F7C8.70; F7C8_70
NCBI Protein Information
EF-TU receptor
NCBI Summary
Encodes a predicted leucine-rich repeat receptor kinase (LRR-RLK). Functions as the receptor for bacterial PAMP (pathogen associated molecular patterns) EF-Tu.
UniProt Synonym Gene Names
EF-Tu receptor
UniProt Protein Name
LRR receptor-like serine/threonine-protein kinase EFR
UniProt Synonym Protein Names
Elongation factor Tu receptor; EF-Tu receptor
UniProt Primary Accession #
C0LGT6
UniProt Secondary Accession #
Q0WWU8; Q8S9I3
UniProt Related Accession #
C0LGT6
UniProt Comments
Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of elongation factor Tu (EF-Tu), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Reduces transformation by Rhizobium radiobacter probably by inducing plant defense during the interaction. Binding to the effector AvrPto1 from P.syringae blocks the downstream plant immune response while interaction with hopD2 decreases the phosphorylation level of EFR upon elf18 treatment. Specific endoplasmic reticulum quality control components (ERD2B, CRT3, UGGT and STT3A) are required for the biogenesis of EFR.