NCBI Accession #
NP_566259.1
NCBI GenBank Nucleotide #
NM_111453.1
NCBI Official Full Name
lon protease 4
NCBI Official Symbol
LON4
NCBI Official Synonym Symbols
F10A16.8; F10A16_8; lon protease 4
NCBI Protein Information
lon protease 4
NCBI Summary
Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins.
UniProt Synonym Gene Names
AtLon4
UniProt Protein Name
Lon protease homolog 4, chloroplastic/mitochondrial
UniProt Primary Accession #
Q9M9L7
UniProt Related Accession #
Q9M9L7
UniProt Comments
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.