NCBI Accession #
NP_565881.1
NCBI GenBank Nucleotide #
NM_129364.4
NCBI Official Full Name
Laccase/Diphenol oxidase family protein
NCBI Official Symbol
IRX12
NCBI Official Synonym Symbols
ARABIDOPSIS LACCASE-LIKE MULTICOPPER OXIDASE 4; ATLMCO4; F16M14.1; F16M14_1; IRREGULAR XYLEM 12; LAC4; LACCASE 4; LACCASE-LIKE MULTICOPPER OXIDASE 4; LMCO4
NCBI Protein Information
Laccase/Diphenol oxidase family protein
NCBI Summary
LAC4 appears to have laccase activity based on enzyme assays performed using lac4 mutants. These mutants also have reduced levels of lignin. LAC4 is expressed in vascular bundles and fibers and likely contributes to lignin biosynthesis, and hence cell wall biosynthesis, there. lac4/irx12 mutants have a mild irregular xylem phenotype.
UniProt Synonym Gene Names
LAC4
UniProt Protein Name
Laccase-4
UniProt Synonym Protein Names
Benzenediol:oxygen oxidoreductase 4; Diphenol oxidase 4; Protein IRREGULAR XYLEM 12; Urishiol oxidase 4
UniProt Primary Accession #
O80434
UniProt Secondary Accession #
Q940U7
UniProt Related Accession #
O80434
UniProt Comments
Lignin degradation and detoxification of lignin-derived products . Required for secondary xylem cell wall lignification.