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Isoprenylcysteine alpha-carbonyl methylesterase ICME (ICME), Recombinant Protein
Cat: RP03522
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Isoprenylcysteine alpha-carbonyl methylesterase ICME (ICME), partial
Product Gene Name
ICME recombinant protein
Product Synonym Gene Name
ICME
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
33,404 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Isoprenylcysteine alpha-carbonyl methylesterase
NCBI/Uniprot Data
NCBI Accession #
NP_197090.2
NCBI GI #
22326830
NCBI GenBank Nucleotide #
NM_121591.5
NCBI GeneID
831443
NCBI Official Full Name
prenylcysteine methylesterase
NCBI Official Symbol
PCME
NCBI Official Synonym Symbols
ATPCME; F14F8.240; F14F8_240; ICME; Isoprenylcysteine methylesterase; prenylcysteine methylesterase
NCBI Protein Information
prenylcysteine methylesterase
NCBI Summary
Encodes a protein with prenylcysteine methylesterase activity.
UniProt Gene Name
ICME
UniProt Synonym Gene Names
PCME; AtPCME
UniProt Protein Name
Isoprenylcysteine alpha-carbonyl methylesterase ICME
UniProt Synonym Protein Names
Isoprenylcysteine methylesterase; Prenylcysteine methylesterase; AtPCME
UniProt Primary Accession #
Q94AS5
UniProt Secondary Accession #
Q9LFU2; F4KBA0
UniProt Related Accession #
Q94AS5
UniProt Comments
Catalyzes the demethylation of isoprenylcysteine methylesters. In vitro, is specific for N-acetyl-S-farnesyl-L-cysteine methyl ester (AFCme) and has low activity toward N-acetyl-S-geranyl-L-cysteine methyl ester (AGCme). Acts as a positive regulator of ABA signaling. May be involved in the demethylation and inactivation of isoprenylated negative regulators of abscisic acid (ABA) signaling. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins.
For research use only, not for clinical use.