NCBI Accession #
NP_192641.2
NCBI GenBank Nucleotide #
NM_116971.6
NCBI Official Full Name
isoamylase 3
NCBI Official Symbol
ISA3
NCBI Official Synonym Symbols
ATISA3; F23J3.50; F23J3_50; isoamylase 3
NCBI Protein Information
isoamylase 3
NCBI Summary
Encodes an isoamylase-like protein. Mutant studies show that the gene is strongly involved in starch breakdown. A GUS-protein fusion product was shown to localize to the surface of chloroplastic structures reminiscent of starch granules. In the mutants, the chloroplastic alpha-amylase AMY3 is upregulated.
UniProt Synonym Gene Names
AtISA3
UniProt Protein Name
Isoamylase 3, chloroplastic
UniProt Primary Accession #
Q9M0S5
UniProt Secondary Accession #
Q8RWW6
UniProt Related Accession #
Q9M0S5
UniProt Comments
Involved in starch catabolism. ISA3 removes different branches than ISA1-ISA2, namely short chains that prevent amylopectin crystallization. May be the debranching enzyme required to assist beta-amylases for starch degradation in leaves at night.