NCBI Accession #
NP_001326318.1
NCBI GenBank Nucleotide #
NM_001339615.1
NCBI Official Full Name
ROP interactive partner 4
NCBI Official Symbol
RIP3
NCBI Official Synonym Symbols
Microtubule Depletion Domain 1; MIDD1; RIP4; ROP interactive partner 3; ROP interactive partner 4
NCBI Protein Information
ROP interactive partner 4
NCBI Summary
Encodes RIP3 (ROP interactive partner 3), a microtubule-binding protein that is anchored to the plasma membrane domains and promotes local microtubule disassembly, forming as specific pattern of secondary walls in xylem vessel cells. Localized at microtubules and interacts with the plant-specific kinesin AtKinesin-13A.
UniProt Synonym Gene Names
MIDD1; RIP3
UniProt Protein Name
Interactor of constitutive active ROPs 5
UniProt Synonym Protein Names
Protein MICROTUBULE DEPLETION DOMAIN 1; ROP-interactive partner 3
UniProt Primary Accession #
Q8VYU8
UniProt Secondary Accession #
Q9LFI2
UniProt Related Accession #
Q8VYU8
UniProt Comments
ROP effector binding specifically activated ROPs and linking them to the microtubule cytoskeleton. Involved in ROP-regulated polar growth. Involved in local disassembly of cortical microtubules when associated with ARAC10 and KIN13A and conversely mediates also the elimination of ARAC10 from the plasma membrane by the cortical microtubules. Accumulates at the plus end of shrinking microtubules. Targets KIN13A to microtubules.