Inositol-tetrakisphosphate 1-kinase 3 (ITPK3), Recombinant Protein
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Inositol-tetrakisphosphate 1-kinase 3 (ITPK3), Recombinant Protein

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Cat: RP03984
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Inositol-tetrakisphosphate 1-kinase 3 (ITPK3)
Product Gene Name
ITPK3 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MFGTLASGEI ETARLNRNLG ITSNLGVSCG GFEDFAMRFE GENMVPYKGE EQEEEEDQVV VNETTPFQFQ QPLFLQQQQK LVVGYALTSK KKKSFLQPKL ELLARRKGIF FVAIDLNRPL SEQGPFDVVL HKLLGKEWEE VIEDYQQKHP EVTVLDPPGS IQRIYNRQSM LQGMADLKLS DCSGSLFVPK QMVVLKDSAA SADAVVEAGL KFPLVAKPLW IDGTAKSHQL YLAYDRRSLA ELDPPLVLQE FVNHGGVMFK VFVVGDVIKV MRRFSLPNVS NCEKAKVDGV FQFPRVSSAA ASADNADLDP RVAELPPKPF LEALVKELRS LLGLRLFNID MIREHGSKNV FYVIDINYFP GYGKLPDYEQ VFVDFFQNLA QVKYKKRQHC K
Sequence Positions
1-391, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
44,172 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Inositol-tetrakisphosphate 1-kinase

NCBI/Uniprot Data

NCBI Accession #
NP_195103.3
NCBI GI #
42567363
NCBI GenBank Nucleotide #
NM_119535.5
NCBI GeneID
829519
NCBI Official Full Name
Inositol 1,3,4-trisphosphate 5/6-kinase family protein
NCBI Official Symbol
AT4G33770
NCBI Official Synonym Symbols
3; 4-trisphosphate 5/6 kinase 2; inositol 1; ITPK2; T16L1.260; T16L1_260
NCBI Protein Information
Inositol 1,3,4-trisphosphate 5/6-kinase family protein
UniProt Gene Name
ITPK2
UniProt Synonym Gene Names
AtItpk-2; Inositol-triphosphate 5/6-kinase 2; Ins(1,3,4)P(3) 5/6-kinase 2
UniProt Protein Name
Inositol-tetrakisphosphate 1-kinase 2
UniProt Synonym Protein Names
Inositol 1,3,4-trisphosphate 5/6-kinase 2 (EC:2.7.1.159
UniProt Primary Accession #
O81893
UniProt Secondary Accession #
Q058I3
UniProt Related Accession #
O81893
UniProt Comments
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 to form InsP5 (PubMed:17698066). This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca2+-activated Cl- channels, while Ins(1,3,4,5,6)P5 is not . Also phosphorylates Ins(1,3,4)P3 or a racemic mixture of Ins(1,4,6)P3 and Ins(3,4,6)P3 to form InsP4 (PubMed:17698066). Ins(1,3,4,6)P4 is an essential molecule in the hexakisphosphate (InsP6) pathway . Plays a role in seed coat development and lipid polyester barrier formation (PubMed:23595027).

For research use only, not for clinical use.