NCBI Accession #
NP_195455.1
NCBI GenBank Nucleotide #
NM_119902.4
NCBI Official Full Name
Auxin-responsive GH3 family protein
NCBI Official Symbol
BRU6
NCBI Official Synonym Symbols
AUR3; AUXIN UPREGULATED 3; F6G17.40; F6G17_40; GH3-2; GH3.2; YADOKARI 1; YDK1
NCBI Protein Information
Auxin-responsive GH3 family protein
NCBI Summary
Encodes an IAA-amido synthase that conjugates Asp and other amino acids to auxin in vitro. Lines carrying insertions in this gene are hypersensitive to auxin. May function as a negative component in auxin signaling by regulating auxin activity.
UniProt Synonym Gene Names
BRU6; CF4; YDK1; AtGH3-2
UniProt Protein Name
Indole-3-acetic acid-amido synthetase GH3.2
UniProt Synonym Protein Names
Auxin-responsive GH3-like protein 2; AtGH3-2; Protein YADOKARI 1
UniProt Primary Accession #
Q9SZT9
UniProt Secondary Accession #
Q93Z39; Q9SLU3; F4JS15
UniProt Comments
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates.