NCBI Accession #
NP_174134.1
NCBI GenBank Nucleotide #
NM_102578.4
NCBI Official Full Name
Auxin-responsive GH3 family protein
NCBI Official Symbol
GH3.17
NCBI Official Synonym Symbols
F3H9.21; F3H9_21
NCBI Protein Information
Auxin-responsive GH3 family protein
NCBI Summary
encodes an IAA-amido synthase that conjugates Asp and other amino acids to auxin in vitro. Lines carrying insertions in this gene are hypersensitive to auxin.
UniProt Synonym Gene Names
AtGH3-17
UniProt Protein Name
Indole-3-acetic acid-amido synthetase GH3.17
UniProt Synonym Protein Names
Auxin-responsive GH3-like protein 17; AtGH3-17
UniProt Primary Accession #
Q9FZ87
UniProt Related Accession #
Q9FZ87
UniProt Comments
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Appears to favor Glu over Asp while the other GH3 favor Asp over Glu. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates.