Hydroxyacylglutathione hydrolase 3, mitochondrial (GLY3), Recombinant Protein
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Hydroxyacylglutathione hydrolase 3, mitochondrial (GLY3), Recombinant Protein

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Cat: RP02658
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Hydroxyacylglutathione hydrolase 3, mitochondrial (GLY3)
Product Gene Name
GLY3 recombinant protein
Product Synonym Gene Name
GLY3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
LFRQLFENES STFTYLLADV SHPDKPALLI DPVDKTVDRD LKLIDELGLK LIYAMNTHVH ADHVTGTGLL KTKLPGVKSV ISKASGSKAD LFLEPGDKVS IGDIYLEVRA TPGHTAGCVT YVTGEGADQP QPRMAFTGDA VLIRGCGRTD FQEGSSDQLY ESVHSQIFTL PKDTLIYPAH DYKGFEVSTV GEEMQHNPRL TKDKETFKTI MSNLNLSYPK MIDVAVPANM VCGLQDVPSQ AN
Sequence Positions
53-294, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
32,332 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Persulfide dioxygenase

NCBI/Uniprot Data

NCBI Accession #
NP_564636.2
NCBI GI #
145336707
NCBI GenBank Nucleotide #
NM_104236.5
NCBI GeneID
841793
NCBI Official Full Name
glyoxalase II 3
NCBI Official Symbol
GLY3
NCBI Official Synonym Symbols
ETHE1; ETHE1-LIKE; ETHYLMALONIC ENCEPHALOPATHY PROTEIN1; F22G10.9; GLX2-3; GLYOXALASE 2-3; glyoxalase II 3; glyoxalase II 3; T3F20.11; T3F20_11
NCBI Protein Information
glyoxalase II 3
NCBI Summary
Mononuclear Fe(II)-containing member of the b-lactamase fold superfamily. ETHE1 is homodimeric in solution, exhibits low-level esterase activity, and specifically binds a single Fe(II) atom in the active site.
UniProt Gene Name
GLY3
UniProt Synonym Gene Names
Glx II
UniProt Protein Name
Persulfide dioxygenase ETHE1 homolog, mitochondrial
UniProt Synonym Protein Names
Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1
UniProt Primary Accession #
Q9C8L4
UniProt Secondary Accession #
Q93VR2; Q96332; Q9LPH3
UniProt Related Accession #
Q9C8L4
UniProt Comments
Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H2S) gives rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H2S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. Required for normal endosperm development in seed, and thereby also required for normal embryo development.

For research use only, not for clinical use.