Unspecific cross-reactions at 40-50 kDa
HSF1 is a key regulator of stress response. It is hyperphosphorylated after heat shock (causing the HSF1 protein to transfer to a slightly higher molecular weight), and the HSF1 protein accumulates rapidly during heat stress. HSF1 appears to exist in the form of high molecular weight complexes, possibly trimers. It also interacts with cytoplasmic HSP70A.
For research use only, not for clinical use.