NCBI Accession #
NP_849984.1
NCBI GenBank Nucleotide #
NM_179653.4
NCBI Official Full Name
homogentisate phytyltransferase 1
NCBI Official Symbol
HPT1
NCBI Official Synonym Symbols
ATHPT; F19F24.15; F19F24_15; HOMOGENTISATE PHYTYLTRANSFERASE; homogentisate phytyltransferase 1; TOCOPHEROL PHYTYLTRANSFERASE; TOCOPHEROL POLYPRENYLTRANSFERASE; TPT1; VITAMIN E 2; VTE2
NCBI Protein Information
homogentisate phytyltransferase 1
NCBI Summary
Encodes homogentisate phytyltransferase involved in tocopherol biosynthesis. Has impact on seed longevity and plays a role in the adaptation to low temperature stress, notably phloem loading.
UniProt Synonym Gene Names
TPT1; VTE2-1; AtHPT1; AtVTE2-1
UniProt Protein Name
Homogentisate phytyltransferase 1, chloroplastic
UniProt Synonym Protein Names
Tocopherol polyprenyltransferase 1; Vitamin E pathway gene 2-1 protein; AtVTE2-1
UniProt Primary Accession #
Q8VWJ1
UniProt Secondary Accession #
O64625
UniProt Related Accession #
Q8VWJ1
UniProt Comments
Involved in the synthesis of tocopherol (vitamin E). Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydrquinone. Low activity with geranylgeranyl diphosphate as substrate, but no activity with farnesyl diphosphate or solanesyl diphosphate. Tocopherol functions to limit lipid oxidation during seed desiccation, quiescence and germination and early seedling development. Protects thylakoid membrane lipids from photooxidation and is required for low-temperature adaptation.